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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
SH5-07 Influence on protein binding to DNA EMSA 0.50 µM NIH3T3/v-Src Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA EMSA 1.00 µM NIH3T3/v-Src Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA EMSA 2.00 µM NIH3T3/v-Src Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA EMSA 5.00 µM NIH3T3/v-Src Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA EMSA 10.00 µM NIH3T3/v-Src Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA EMSA 20.00 µM NIH3T3/v-Src Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 1.00 µM NIH3T3/hEGFR Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 3.00 µM NIH3T3/hEGFR Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 5.00 µM NIH3T3/hEGFR Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 10.00 µM NIH3T3/hEGFR Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 20.00 µM NIH3T3/hEGFR Mus musculus STAT3:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 1.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 3.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 5.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 10.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 20.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT3
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 1.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT1
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 3.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT1
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 5.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT1
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 10.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT1
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 20.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT1
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 1.00 µM NIH3T3/hEGFR Mus musculus STAT5:STAT5
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 3.00 µM NIH3T3/hEGFR Mus musculus STAT5:STAT5
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 5.00 µM NIH3T3/hEGFR Mus musculus STAT5:STAT5
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 8.00 µM NIH3T3/hEGFR Mus musculus STAT5:STAT5
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 10.00 µM NIH3T3/hEGFR Mus musculus STAT5:STAT5
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 15.00 µM NIH3T3/hEGFR Mus musculus STAT5:STAT5
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 20.00 µM NIH3T3/hEGFR Mus musculus STAT5:STAT5
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 8.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT1
SH5-07 Influence on protein binding to DNA in presence of EGF EMSA 15.00 µM NIH3T3/hEGFR Mus musculus STAT1:STAT1
SH5-07 Infleunce on protein activity Western Blot 5.00 µM NIH3T3/v-Src Mus musculus p-STAT3 (Y705)
SH5-07 Infleunce on protein activity Western Blot 5.00 µM NIH3T3/v-Src Mus musculus STAT3
SH5-07 Infleunce on protein activity in transfected cells Luciferase activity 3.00 µM NIH3T3 pLucTKS3 Mus musculus
SH5-07 Infleunce on protein activity in transfected cells Luciferase activity 8.00 µM NIH3T3 pLucTKS3 Mus musculus
SH5-07 Infleunce on protein activity in transfected cells Luciferase activity 3.00 µM NIH3T3 pLucSRE Mus musculus
SH5-07 Infleunce on protein activity in transfected cells Luciferase activity 8.00 µM NIH3T3 pLucSRE Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 2.00 µM NIH3T3/v-Src Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 4.00 µM NIH3T3/v-Src Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 6.00 µM NIH3T3/v-Src Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM NIH3T3/v-Src Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 10.00 µM NIH3T3/v-Src Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 2.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 4.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 6.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 8.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell viability CyQUANT cell proliferation assay 10.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell motility Colony formation assay 1.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell motility Colony formation assay 3.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell cycle Flow cytometry- propodium iodide 3.00 µM MEF/ST3KO Mus musculus
SH5-07 Influence on cell cycle Flow cytometry- propodium iodide 5.00 µM MEF/ST3KO Mus musculus